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The Open Protein Structure Annotation Network
PDB Keyword
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3c5y

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of putative ribose 5-phosphate isomerase (YP_001165900.1) from Novosphingobium aromaticivorans DSM 12444 at 1.81 A resolution. To be published
    Site JCSG
    PDB Id 3c5y Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS1745,YP_001165900.1, 86622
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 16
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 2.31 Rfactor 0.170
    Waters
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    Solvent Content 46.74

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 3c5y
    1. The translation regulatory subunit eIF3f controls the kinase-dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse
    A Csibi, K Cornille, MP Leibovitch, A Poupon - PloS one, 2010 - dx.plos.org
     
    2. Structures of type B ribose 5_phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family
    AL Stern, A Naworyta, JJ Cazzulo, SL Mowbray - FEBS Journal, 2011 - Wiley Online Library
     
    3. Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis
    TE Edwards, AB Abramov, ER Smith - BMC structural , 2011 - biomedcentral.com
     
    4. For Review Only
    A Naworyta, T de Chascoms, S Mowbray - FEBS Journal, 2011 - uu.diva-portal.org
     

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    Protein Summary

    Gene Saro_3514 from Novosphingobium aromaticivorans dsm 12444 encodes the YP_001165900 protein that belongs to Ribose/Galactose Isomerase  group (PF02502). This family of proteins contains the sugar isomerase enzymes ribose 5-phosphate isomerase B (rpiB), galactose isomerase subunit A (LacA) and galactose isomerase subunit B (LacB).

    SCOP classifies 3c5y in the alpha/beta class, ribose/galactose isomerase RpiB/AlsB (super)family. 3c5y fold consists of a sheet flanked by several helices. According to DALI, there are several structures with significant similarity to 3c5y, all ribose phosphate isomerases:

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    (Z-scr=34),
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    (Z-scr=17),
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    (Z-scr=16).

    Ligand Summary

    Nitrate and Ethylene glycol from the crystallization/cryo conditions.

    References

    Reviews

    References

     

    No references found.

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