The Open Protein Structure Annotation Network
PDB Keyword


    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of a putative acetyltransferase (NP_394282.1) from Thermoplasma acidophilum at 2.00 A resolution. To be published
    Site JCSG
    PDB Id 3c26 Target Id 376023
    Molecular Characteristics
    Source Thermoplasma acidophilum dsm 1728
    Alias Ids TPS1664,NP_394282.1, 336968 Molecular Weight 30521.85 Da.
    Residues 265 Isoelectric Point 5.31
    Sequence msadivfdrgspsdideiktftsntwkvgyytdlyskladtgtmddyvdkvierwvndgsvyvlrvsgr pvatihmeklpdgsvmlgglrvhpeyrgsrlgmsimqetiqflrgkterlrsavyswnepslrlvhrlg fhqveeypiytfqggstavpalkpvneryagrwrcffidwkymcsddpdiiheeysnnlivdgstfvyf diyeggidlfvndsddassfiekyrsmngritfyvrkalanglpyvpassltvweyry
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 1
    Resolution (Å) 2.00 Rfree 0.242
    Matthews' coefficent 2.04 Rfactor 0.179
    Waters 150 Solvent Content 39.85

    Ligand Information


    Google Scholar output for 3c26
    1. Measured and calculated CD spectra of G_quartets stacked with the same or opposite polarities
    DM Gray, JD Wen, CW Gray, R Repges, C Repges - Chirality, 2008 - Wiley Online Library
    2. Circular Dichroism Spectra and Electrophoretic Mobility Shift Assays Show That Human Replication Protein A Binds and Melts Intramolecular G-Quadruplex Structures
    JH Fan, E Bochkareva, A Bochkarev, DM Gray - Biochemistry, 2009 - ACS Publications
    3. Re-Annotation of Two Hyperthermophilic Archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638
    J Gao, J Wang - Current microbiology, 2012 - Springer

    Protein Summary

    376023 belongs to the acetyltransferase (GNAT) family, which is PF00583. It is structurally similar to other acetyltransferases, including 1b87 as well as the N-acetyl transferase, NAT family from SCOP.

    376023 crystallizes as a monomer, but is predicted to form a dimer in solution.

    Ligand Summary





    No references found.

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