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3b7c

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of NTF-2 like protein of unknown function (NP_715767.1) from Shewanella oneidensis at 1.70 A resolution. To be published
    Site JCSG
    PDB Id 3b7c Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS1717,NP_715767.1, 3.10.450.50, 92079
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 1
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 2.75 Rfactor 0.184
    Waters
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    Solvent Content 55.32

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 3b7c
    1. Dimensionality reduction in computational demarcation of protein tertiary structures
    RR Joshi, PR Panigrahi, RN Patil - Journal of Molecular Modeling, 2011 - Springer
     

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    Protein Summary

    SO_0125 gene from Shewanella oneidensis encodes the NP_715767.1 protein. It shows insignificant sequence similarity to PF08332. The gene fusion of SO_0125 with the asparaginase family protein SO_2115 indicates the functional association with this medically important protein family. The function of SO_0125 genomic neighbor (SO_0124) is unknown.

    SCOP classifies 3b7c in the alpha+beta class, cystatin-like fold, NTF2-like superfamily. According to DALI, 3b7c has a structure similar to proteins with PDB codes 3hx8 (Z=17), 3cu3 (Z=16), 2r4i (Z=15), 1oun (Z=14), 1tp6 (Z=14), 1hkx (Z=14). It is likely that 3b7c forms a dimer in solution. More analysis is needed to see if the dimer could further multimerize into a tetradecameric assembly as does the association domain of Ca2+/calmodulin-dependent kinase II (CaMKII, PDB code 1hkx).

    Ligand Summary



    References

    Reviews

    References

     

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