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The Open Protein Structure Annotation Network
PDB Keyword
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2pc1

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of acetyltransferase GNAT family (NP_688560.1) from Streptococcus agalactiae 2603 at 1.28 A resolution. To be published
    Site JCSG
    PDB Id 2pc1 Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS1585,NP_688560.1, BV1424C, 92851
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 1
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 1.97 Rfactor 0.167
    Waters
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    Solvent Content 37.68

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 2pc1
    1. Expansion of the protein repertoire in newly explored environments: human gut microbiome specific protein families
    K Ellrott, L Jaroszewski, W Li, JC Wooley - PLoS computational , 2010 - dx.plos.org
     
    2. Evolution of insect arylalkylamine N-acetyltransferases: Structural evidence from the yellow fever mosquito, Aedes aegypti
    Q Han, H Robinson, H Ding - Proceedings of the , 2012 - National Acad Sciences
     

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    Protein Summary

    Gene SAG1567 translates into the NP_688560.1 amino acid sequence that corresponds to a single domain protein with a low homology (e-val=6e-4) to the acetyltransfersase GNAT family (PF00583). It has a weak (score 0.66) genome context link with NP_688559, a 2-hydroxyacid dehydrogenase.

     

    2pc1 structure belongs to the SCOP alpha+beta class, Acyl-Coa N-acyltransferase superfamily, N-acetyltransferase family. The closest structure similarity is with 2fia (FFAS scr=-65; HHpred P-val=1e-34; SSM 77%; Dali Z-scr=20.1; FATCAT P-val=4e-14), 2oh1 (FFAS scr=-64; HHpred P-val=1e-33; Dali Z-scr=17.4) and 3bln (FFAS scr=-50; HHpred P-val=1e-30; SSM 85%; Dali Z-scr=17.8), all bacterial acetyltransferases.

    Ligand Summary


    References

    Reviews

    References

     

    No references found.

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