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2p8g

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of phenolic acid decarboxylase (2635953) from Bacillus subtilis at 1.36 A resolution. To be published
    Site JCSG
    PDB Id 2p8g Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS1574,2635953, PF05870
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 1
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 3.46 Rfactor 0.133
    Waters
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    Solvent Content 64.44

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 2p8g
    1. p_Coumaric acid decarboxylase from Lactobacillus plantarum: Structural insights into the active site and decarboxylation catalytic mechanism
    H Rodrguez, I Angulo, B de las Rivas - Proteins: Structure, , 2010 - Wiley Online Library
     
    2. Structural basis of enzymatic activity for the ferulic acid decarboxylase (FADase) from Enterobacter sp. Px6-4
    W Gu, J Yang, Z Lou, L Liang, Y Sun, J Huang, X Li - PloS one, 2011 - dx.plos.org
     
    3. Structural analysis of Bacillus pumilus phenolic acid decarboxylase, a lipocalin-fold enzyme
    A Matte, S Grosse, H Bergeron, K Abokitse - Section F: Structural , 2010 - scripts.iucr.org
     
    4. Mutational analysis of phenolic acid decarboxylase from Bacillus subtilis (BsPAD), which converts bio-derived phenolic acids to styrene derivatives
    A Frank, W Eborall, R Hyde, S Hart - Catalysis Science & , 2012 - pubs.rsc.org
     

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    Protein Summary

    The padC (yveH) (BSU34400) gene from B. subtilis encodes the protein NP_391320 which is a phenolic acid decarboxylase (PAD) [Ref]. Its amino acid sequence belongs to the family PF05870 and the structure solved here is the K146Y mutant.

     

    SCOP classifies 2p8g inside the all-beta class, lipocalins superfamily, PAD family. The bacterial PAD structures 2gc9, and its related entry 2w2a, scored the highest similarity with 2p8g (FFAS score=-107; SSM 86%; Dali Z-scr=29). 

    Ligand Summary



    References

    Reviews

    References

     

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