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The Open Protein Structure Annotation Network
PDB Keyword
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2onf

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of hypothetical protein (NP_393673.1) from Thermoplasma acidophilum at 1.70 A resolution. To be published
    Site JCSG
    PDB Id 2onf Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS1569,NP_393673.1, 92422
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 2
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 2.39 Rfactor 0.162
    Waters
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    Solvent Content 48.58

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 2onf

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    Protein Summary

    Gene Ta0195 from Thermoplasma acidophilum encodes protein NP_393673 that belongs to the large family of OsmC-like proteins (PF02566, COG1765, and COG1764). Proteins from this family are present mostly in bacteria, but also in protists, slime molds and fungi, are involved in oxidative / osmotic stress response and hydroperoxide detoxification. Interestingly, eukaryotic proteins from this family do not form a common sub-tree and appear to represents independent gene transfer events. In the vicinity of gene Ta0195, a death associated protein kinase related protein is found with score 0.8 (Ta0196)

    According to SCOP, 2onf and its structural similar neighbors (PDB structures [Dali Z score]:

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    [Z=15],
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    [Z=15],
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    [Z=16],
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    [Z=14],
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    [Z=14],
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    [Z=12], and
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    [Z=11]) belong to the OsmC-like fold from the alpha+beta class. Other proteins from this family solved by JCSG are Thermotoga maritima protein TM0919 (
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    , topsan) and
    Psychrobacter arcticus protein Psyc_0566 (
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    , topsan).

    Ligand Summary



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