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The Open Protein Structure Annotation Network
PDB Keyword
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2ogi

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of conserved hypothetical protein TIGR00488 (NP_688652.1) from Streptococcus agalactiae 2603 at 1.85 A resolution. To be published
    Site JCSG
    PDB Id 2ogi Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS1560,NP_688652.1, BIG_3, 91165
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 2
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 2.44 Rfactor 0.172
    Waters
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    Solvent Content 49.63

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 2ogi
    1. Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard
    TC Terwilliger, PD Adams, RJ Read - Section D: Biological , 2009 - scripts.iucr.org
     
    2. Structural and Biochemical Analysis of Nuclease Domain of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Protein 3 (Cas3)
    S Mulepati, S Bailey - Journal of Biological Chemistry, 2011 - ASBMB
     
    3. Structure-based functional inference of hypothetical proteins from Mycoplasma hyopneumoniae
    MM Da Fonsca, A Zaha, ER Caffarena - Journal of Molecular , 2011 - Springer
     

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    Protein Summary

    The SAG1661 of S. agalactiae 2603 encodes the NP_688652 protein, a putative metal dependent phosphohydrolase (PF01966) with very strong sequence similarity to COG1713 (predicted HD superfamily hydrolase involved in NAD metabolism). Analysis of its genome context indicates a likely functional link (score 0.89) with SAG1659, a Iojap-related protein, and SAG1665, a haloacid dehalogenase-like family hydrolase.
     

    2ogi structure belongs to SCOP all alpha class, HD-domain/PDEase-like superfamily, HD domain family. DALI top hits are with the BH1327 protein

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    (Z=28), and the HD hydrolases
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    (Z=27) and
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    (Z=11).

    Ligand Summary

    In the crystal structure SAG1661 interacts with guanosine-5'-diphosphate (GDP), MES and Fe and Cl. For details please see PDBsum server.


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