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PDB Keyword
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2g0t

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of hypothetical protein (tm0796) from Thermotoga maritima at 2.67 A resolution. To be published
    Site JCSG
    PDB Id 2g0t Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS1233,TM0796, PF07755, 3.40.1190.10, 282650, 289589, 90003
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 2
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 3.90 Rfactor 0.207
    Waters
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    Solvent Content 68.22

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 2g0t
    1. X_ray crystal structure of a hypothetical Sua5 protein from Sulfolobus tokodaii strain 7
    Y Agari, S Sato, T Wakamatsu, Y Bessho - Proteins: Structure, , 2008 - Wiley Online Library
     

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    Protein Summary

    The gene TM0796 from Thermotoga maritima  encodes the NP_228605 protein, a member of the DUF1611 group PF07755.  This domain is found in a number of hypothetical bacterial and archaeal (not eukarya) proteins that are part of the  P-loop containing nucleoside triphosphate hydrolase superfamily (CL0023). A member of this family from Methanococcus maripaludis, with 24% seq. id. to TM0796, is the A subunit of (H+)-transporting two-sector ATPase Q6M063 suggesting a chaperone-like function assisting in the assembly/disassembly or operation of protein complexes. TM0796 genome context analysis indicates a possible funtional link (score 0.88) with TM0006, a muconate cycloisomerase.

    SCOP classifies 2g0t in the alpha/beta class, P-loop containing nucleoside triphosphate hydrolases superfamily, nitrogenase iron protein like family. DALI top hit is with another DUF1611 2obn (Z=36). Next is the nucleotide binding protein 3kb1 (Z=14) and the dethiobiotin synthetase 3fpa (Z=13). A molecule of phosphate per chain is found attached to residues V168, V169, G170, K171 and R172 in 2g0t. 

    Ligand Summary


    References

    Reviews

    References

     

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