.
The Open Protein Structure Annotation Network
PDB Keyword
.

1vmj

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of hypothetical protein (TM0723) from Thermotoga maritima at 1.52 A resolution. To be published
    Site JCSG
    PDB Id 1vmj Target Id
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
    Molecular Characteristics
    Source
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
    Alias Ids
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
    TPS1228,TM0723, 84688
    Molecular Weight
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
    Da.
    Residues
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
    Isoelectric Point
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
    Sequence
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
      BLAST   FFAS

    Structure Determination
    Method XRAY
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
    Chains 1
    Resolution (Å)
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
    Rfree
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
    Matthews' coefficent 2.85 Rfactor 0.144
    Waters
    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)
    Solvent Content 56.48

    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)

    Access denied for user 'root'@'localhost' (using password: YES) (click for details)

    Ligand Information
    Ligands
    Metals

    Jmol

     
    parameter 'target' could not convert from 'list' to 'str' (click for details)
    Google Scholar output for 1vmj
    1. Sensitive genome-wide screen for low secondary enzymatic activities: the YjbQ family shows thiamin phosphate synthase activity
    E Morett, G Saab-Rincn, L Olvera, M Olvera - Journal of molecular , 2008 - Elsevier
     
    2. Ligands in PSI structures
    A Kumar, HJ Chiu, HL Axelrod, A Morse - Section F: Structural , 2010 - scripts.iucr.org
     
    3. Crystal structure of the hypothetical protein ST2072 from Sulfolobus tokodaii
    Y Tanaka, K Tsumoto, E Tanabe - Proteins: Structure, , 2005 - Wiley Online Library
     

    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)

    reference to undefined name 'note' Exception of type 'MindTouch.Deki.Script.Runtime.DekiScriptUndefinedNameException' was thrown. (click for details)

    Protein Summary

    The TM0723 gene of Thermotoga maritima encodes a protein of uncharacterized function (PF01894, COG0432). The family shows a wide species distribution with over 500 sequences in over 400 species including eukaryotes (sea anemone, fruit fly, mosquito, tapeworm, fungi, rice and yeast), prokaryotes (actinobacteria, bacteroidetes, chloroflexi and firmicutes) and archaea. A number of other structures solved as part of the worldwide Structural Genomics initiative display strong structural (main-chain rmsd between 0.6-1.8 Å over 118-139 residues) and sequence similarity (sequence identity 31-60%) with TM0723 including 2p6c, 1vph, 2p6h, 1xbf, 1vmf and 2cu5. Pre-SCOP describes the structure as adopting a novel fold termed YjbQ-like.

     

    The protein architecture of another family homolog from smut fungus (Q4PFT5_USTMA) contains PX (PF00787), PH (PF00169) and RhoGAP (PF00620) domains, suggesting a function in signal transduction implicating the cytoskeleton.

     

    Thiamin phosphate synthase activity has been shown [Ref], however this is probably not the primary function of this family.

     

    [check Drosophila, yeast knock-outs/screens]

    Genetic neighborhood:

    TM0723: ribonuclease R, UMP pyrophosphorylase, serine hydroxylmethyltransferase, purine-binding chemotaxis protein, ComM protein (predicted ATPase with chaperone activity)

     

    PH0581: alanyl tRNA synthetase, dimethyladenosine transferase, translation termination factor

    Ligand Summary



    References

    Reviews

    References

     

    1. (No Results)

       


      Discuss this publication

    Files (0)

     
    You must login to post a comment.
    All content on this site is licensed under a Creative Commons Attribution 3.0 License
    Powered by MindTouch