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    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title Crystal structure of Acyl carrier protein (TM0175) from Thermotoga maritima at 2.00 A resolution. To be published
    Site JCSG
    PDB Id 1vku Target Id 282055
    Molecular Characteristics
    Source Thermotoga maritima msb8
    Alias Ids TPS1189,TM0175 Molecular Weight 10284.21 Da.
    Residues 88 Isoelectric Point 4.33
    Sequence merkkliakfveiasekmgkdletvdeentfkelgfdsidvidlvmffedefalriedeeiskirkvkd lidivikkleeiddevseg
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 1
    Resolution (Å) 2.00 Rfree 0.25276
    Matthews' coefficent 2.14 Rfactor 0.19696
    Waters 45 Solvent Content 42.14

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    Ligand Information


    Google Scholar output for 1vku
    1. The Buccaneer software for automated model building. 1. Tracing protein chains
    K Cowtan - Acta Crystallographica Section D: Biological , 2006 - scripts.iucr.org
    2. Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain
    EJ Drake, DA Nicolai, AM Gulick - Chemistry & biology, 2006 - Elsevier
    3. Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation_site sequence
    MA Johnson, W Peti, T Herrmann, IA Wilson - Protein , 2006 - Wiley Online Library
    4. StructureFunction Analysis of the Acyl Carrier Protein Synthase (AcpS) from Mycobacterium tuberculosis
    O Dym, S Albeck, Y Peleg, A Schwarz - Journal of molecular , 2009 - Elsevier
    5. Solution Structure of 4 -Phosphopantetheine-GmACP3 from Geobacter metallireducens: A Specialized Acyl Carrier Protein with Atypical Structural Features and a
    TA Ramelot, MJ Smola, HW Lee, C Ciccosanti - Biochemistry, 2011 - ACS Publications
    6. Performance of phased rotation, conformation and translation function: accurate protein model building with tripeptidic and tetrapeptidic fragments
    F Pavelcik, J Vaclavik - Acta Crystallographica Section D: Biological , 2010 - scripts.iucr.org

    Protein Summary

    The TM0175 gene from Thermotoga maritima encodes an acyl-carrier protein (ACP) (PF00550, COG0236, EC).


    The structure shows strong similarity to the oxytetracycline polyketide synthase ACP from Streptomyces rimosus (PDB id: 1nq4, Findlow 2003) with

    Ligand Summary





    No references found.

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