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The Open Protein Structure Annotation Network
PDB Keyword
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1vjl

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary
    3. 3. References

    Title On the use of DXMS to produce more crystallizable proteins: structures of the T. maritima proteins TM0160 and TM1171. Protein Sci. 13 3187-3199 2004
    Site JCSG
    PDB Id 1vjl Target Id
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    Molecular Characteristics
    Source
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    Alias Ids
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    TPS1186,TM0160, 89344
    Molecular Weight
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    Da.
    Residues
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    Isoelectric Point
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    Sequence
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      BLAST   FFAS

    Structure Determination
    Method XRAY
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    Chains 2
    Resolution (Å)
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    Rfree
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    Matthews' coefficent 2.45 Rfactor 0.198
    Waters
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    Solvent Content 49.30

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    Ligand Information
    Ligands
    Metals

    Jmol

     
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    Google Scholar output for 1vjl
    1. On the use of DXMS to produce more crystallizable proteins: structures of the T. maritima proteins TM0160 and TM1171
    G Spraggon, D Pantazatos, HE Klock, IA Wilson - Protein , 2004 - Wiley Online Library
     
    2. An iterative knowledge_based scoring function for proteinprotein recognition
    SY Huang, X Zou - Proteins: Structure, Function, and , 2008 - Wiley Online Library
     
    3. Prediction of active sites for protein structures from computed chemical properties
    J Ko, LF Murga, Y Wei, MJ Ondrechen - Bioinformatics, 2005 - Oxford Univ Press
     
    4. Discovery of a thermophilic protein complex stabilized by topologically interlinked chains
    DR Boutz, D Cascio, J Whitelegge, LJ Perry - Journal of molecular , 2007 - Elsevier
     
    5. A segment of cold shock protein directs the folding of a combinatorial protein
    S De Bono, L Riechmann, E Girard - Proceedings of the , 2005 - National Acad Sciences
     

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    Protein Summary

    The TM0160 gene ( PF02577, cl00553) from Thermotoga maritima MSB8 encodes for the NP_227975 protein of unknown function (DUF151). Hits detected by HHpred and FFAS are not reliable enough to derive a meaningful annotation. Analysis of its genome context shows (score 0.87) the presence of a geranyltrans-transferase (TM0161).

    1vjl is the first structure of this family to be experimentally determined and revealed a novel fold (SCOP alpha+beta class, TM0160 fold). DALI only very weak hit (Z=4) is with the NE1496 protein 2fbl. This family has been brought into connection with the DNA damage recognition domain DVR [Ref]. PDB structure 1VJL replaced 1O5Y. PDB structure 1VJL contains the sequence of 1SJ5.

    Ligand Summary



    References

    Reviews

    References

     

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